Oral cancer thesis pdf

Balakrishnan, nyla 2018, legally authorized representatives awareness of the oral health needs of long term care facility residents. The thesis is the backbone for all the other arguments in your essay, so it has to cover them all. From carcinogenesis to metastasis by bogumi l kaczkowski a dissertation submitted in partial satisfaction of the requirements for the degree of doctor of philosophy in bioinformatics at the phd school of science, faculty of science, university of copenhagen, denmark. This thesis reflects on both epidemiology and prognostic factors in the context of oral and oropharyngeal squamous cell carcinoma oophscc. In india, with high rates of oral cancer, the rates of tonsillar cancer were between 0.

Clinical and statistical studies showed that this illness is correlated to smoking and alcohol intake. This thesis focuses on molecular biomarker expression in otscc. Although early diagnosis is relatively easy, presentation with advanced disease is not uncommon. Perceptions of breast symbolism, societal and personal, were explored, as were perceptions of the external portrayal of their. Surgeryin patients with an oral or oropharyngeal cancer, the extent of resection of the oral tongue and tongue base has been found to be related to swallowing ability. Oral cancer, nextgeneration sequencing, tobacco, human papilloma virus. With respect to t category depth of invasion doi has been added with cutoff points of less than 5 mm, 510 and. Thesis submitted to the university of london for the degree of md. Oral cancer essay oral cancer is a devastating disease. The back of the tongue base of the tongue, the back of the roof of the mouth soft palate, and the tonsils are not considered part of the oral cavity. May 25, 2016 yes, the answer to this question depends on your situation.

Introduction the term oral cancer encompasses all malignancies that originate in the oral tissues. Full hpv science articles pdfs the oral cancer foundation. Oral tongue cancer constitutes the majority of malignancies of the oral cavity. As documented the phenotypic changes of oral cancer is always preceded by genetic damages accumulated due to various carcinogens. Oral cancer includes cancer of the lip, tongue, salivary glands plus other sites in the mouth. Oral health refers to the health of the teeth, gums, and the entire oral facial system that allows us to smile, speak, and chew. Oral carcinoma of the retromolar trigone, maxillary. Oral cancer is the 11th most common cancer in the world, accounting for an estimated 300,000 new cases and 145,000 deaths in 2012 and 702,000 prevalent cases over a period of five years old and new cases tables 5.

Oral squamous cell carcinoma oscc is an aggressive and unpredictable cancer with a high tendency to recur and metastasise. Introduction oral cancer or oral squamous cell carcinoma oscc is among the most common types of cancer in india and strongly linked to habits like smoking and smokeless tobacco, alcohol and areca nut chewing. Squamous cell carcinoma of the oral cavity comprises 90. University of pretoria masters dissertation the incidence of oral and oropharyngeal cancer in south africa for the five year period 19972001 muhammed hanif abram. Balm, this thesis deals with the function and infiltrative capacity of mononuclear phagocytes in head and neck cancer.

Interplay between keratin and vimentin expression in oral. Casway a thesis submitted to the johns hopkins university in conformity with the requirements for the degree of master of arts. Epidemiology of oral cancer from a socioeconomic perspective. The earlier the cancer is detected, the easier the treatment and the greater the chance of a cure. Particularly in the detection, evaluation and management of early phase alterations or frank disease. Oral cancer thesis topics brave new world and 1984 essay topics. Some cancer types, even though disseminated, such as leukemias and lymphomas in children, and testicular. It is a challenging disease in its nature and management affecting not. Andrew yeudall philips institute, vcu school of dentistry. The standard of care is primary surgical resection with or without postoperative adjuvant therapy. Contraception myths and their influences a focus group approach by stephanie j. The role of these genetic mechanisms in oral cancer appears complex. Majority of these studies have been casecontrol 28 of 33 while only five three from sear and two from eur were cohort studies.

Risk factors for oral cancer, a retrospective study among. Dental public health theses and dissertations preventive. While you may be asked to write on a series of potential topics, there are similarities in all of the possible subjects. Im looking for a rat oral cancer cell line to produce tumor in the oral cavity preferably in the tongue of healthy immunocompetent sd or wistar rats. Thesisproject proposal museum and exhibition studies. Finally, on page 28, the paper looks at the practical implementation of a cancer screening strategy.

While both women and men can also get the breast cancer disease there is a cure with awareness to breast cancer. The oral cavity and oropharynx, along with other parts of the head and neck, give us the ability to chew, swallow, breathe, and talk. Cancer of the oral cavity is a most devastating disease that causes a significant disfigurement of the patient. Oral cancer is the sixth most common cancer in the world, and it continues to represent a serious public health problem. Multidisciplinary treatment is crucial to improve the oncologic and functional results in oral cancer patients. Citescore values are based on citation counts in a given year e. About two thirds of patients with this disease have advanced stage 5. Treatment of other cancers with potential for cure. These critical points include the generation of cancer, the effect of cancer on a cells function, proliferation, tumor growth and development, avenues for preventing the spread of cancer. Research paper increased prevalence of esophageal cancer.

Also discover topics, titles, outlines, thesis statements, and conclusions for your cancer treatment essay. Because oc is one of the leading malignancies in taiwan, the government has conducted an oc screening project for the public. Interplay between keratin and vimentin expression in oral cancer by mary catherine mcginn, m. Abstract the cancer immunosurveillance hypothesis postulates that the immune system can recognize cancer cell precursors and destroy those cells before a clinical manifestation occurs.

Metabolic reprogramming of human lung cancer cells and ex vivo tissues revealed by uhrftms analysis of small amino and carboxyl metabolites, ye yang. Young women with breast cancer study breast cancer than their older counterparts. Nickel is probably a common environmental risk factor foresophageal cancer and oral cancer. Early intervention gives, as with many types of cancer, the best prognosis. History of oral cancer research initiative associate dean. A prospective parallel design study testing noninferiority of customized oral stents made using 3d printing or manually fabricated methods. Speech and swallowing rehabilitation for head and neck. View and download cancer treatment essays examples. In this thesis, we preclinically evaluated various novel antibodybased agents that were designed to improve the tumorselective action of cancer immunotherapy. Breast cancer and who it attacks a what is the disease and who it affects 1. Cancer of the oral cavity is one of the most common malignancies, 1 especially in developing countries, but also in the developed world 2. Some of the most common diseases that impact our oral health include tooth decay cavities, gum periodontal disease, and oral cancer. In the united states, 90% of the risk for developing oral cavity cancer is directly attributed to smoking shopland and. Histopathological predictors of early stage oral tongue cancer.

The overarching aim of this thesis is to investigate the epidemiology of oral cancer in relation to individual socioeconomic status, areabased socioeconomic. Research on cancer and particularly oral cancer aetiology has somewhat overlooked this area, in favour of pursuing genetic and lifestyle risk factors. Oral health conditions division of oral health cdc. Pdf smokeless tobacco paan and gutkha consumption and. Risk factors for oral hpv persistence and hpvassociated cancer by jennifer o. A doctor or dentist usually finds oral cancer in its early stages because the mouth can be easily examined. In totality, this thesis suggests that public health policy to address the overall rising incidence and widening inequalities of oral cancer needs to acknowledge the complexity of the risk factors. Phd thesis all chapters final revisions jerry machado tspace.

Research paper increased prevalence of esophageal cancer in. Oral cancer foundation, national cancer institute, national institutes of health oral cancer fact sheet american association of oral and maxillofacial surgeons. Overcoming treatment resistance in heterogeneous tumors, nikhil. Despite increasing efforts to improved treatment, the 5year survival rate is still low.

Since good oral health is essential to good overall health as well as to the prevention of oral disease and unnecessary suffering, oral health is a major concern of local public health agencies lphas. This open access thesis is brought to you for free and open access by the school of medicine at. Theses and dissertationstoxicology and cancer biology. University of groningen novel antibodybased drugs for pd. Oral cancer is cancer that starts in the mouth or throat. Oral cancer is a cancer that begins in the mouth or the throat at the back of the mouth. Cancer is when cells in the body change and grow out of control. Role of the plasminogen activation system in tumour progression. Gene expression analysis in breast cancer jai prakash mehta ph. In finland during 20, the ageadjusted incidence rates of oral tongue cancer were 1.

Overall incidence worldwide for males has been estimated at 6. Oral lichen planus leukoplakia oral cancer immunosurveillance solid organ transplantation t cells langerhans cells. Virginia commonwealth university, 2010 major director. Expression of zeb factors in oral squamous cell carcinoma. Nickel is an essential metal used in many industries, including electroplating. Hpv associated oral lesions library dissertation dr. Role of sulfiredoxin interacting proteins in lung cancer development, hedy chawsheen. The research work described in thesis was performed under the supervision of dr. The main objectiveswere to assess a number of in vitro functions of peripheral monocytes in patients suffering. Patients have many different learning styles so educational tools should be tailored to support them. Cancer that appears in tissues of the mouth or the region of the throat located at the back of the mouth the oropharynx, is considered to be oral cancer. About 40% of head and neck malignancies are known to be squamous cell carcinomas arising in the oral cavity 2. You will need to complete citi training, and submit your research proposal to the oprs office for determination regarding the.

Risk factors for oral cancer, a retrospective study among an indian population. Quality of life of head and neck cancer patients after tumor. Home school of public health public health theses digital library. Autofluorescence guided surveillance for oral cancer american association for cancer research oral cancer knowledge, attitudes and practices the journal of the american dental association value of visual screenings study world health organization managing mucositis elsevier publishing directtoconsumer advertising for oral cancer screening devices. Oral cancer is a preventable disease, related to behavioral and lifestyle. Quality of life of head and neck cancer patients after. Recent oral oncology articles recently published articles from oral oncology.

M mononuclear phagocyte function in head and neck cancer. The overarching aim of this thesis was to investigate the epidemiology of oral cancer in relation to individual socioeconomic status ses, areabased socioeconomic circumstances, and. The incidence of oral and oropharyngeal cancer in south africa for the five. Squamous cell carcinoma scc is the most common histology and the main etiological factors are tobacco and alcohol use 3. Oral cancer is a type of head and neck cancer and is any cancerous tissue growth located in the oral cavity1. Oral cancer can affect a majority of regions on your body, including your lips, tongue, the inside of your mouth, your jaws, throat, ears, face, and neck. The cell biological basis of cancer miami university. International agency for research on cancer iarc indicated that the lip and oral cavity is the tenth most common tumor site in the human organism. Thesis on oral cancer and bangladesh by roushan zadeed issuu. A guide for developing and enhancing community oral health. Though the diagnosis of oral cancer seldom presents difficulty, it is the early detection, cancer staging and histological grading that are more important for prognosis. Staging of the clinical status of tumor size, lymph node, and metastasis. A thesis submitted in partial fulfillment of the requirements for the degree of master of science at virginia commonwealth university. Oral cancer is divided into two categories those occurring in the oral cavity your lips, the inside of your lips and cheeks, teeth, gums, the front twothirds of your tongue and the floor and roof of your mouth and those occurring in the oropharynx middle region of the throat, including the tonsils and base of the tongue.

As a result, many oc patients were diagnosed at an early stage and had a. The study of green grass is popular among agrostologists. Opportunities for achieving early diagnosis of oral cancer within the. Oral cancer is fairly common and very curable if found and treated at an early stage. Oral cancer is the eighth most common cancer worldwide, with an estimated 405 318 newly diagnosed cases in 2002. The aim of this thesis was to investigate if the clinical impression of increased incidence of tonsillar cancer was true, and if hpv could be linked to this increase. Faculty of health sciences, department of medical biology.

Dear mandana donoghue, there are changes in this edition concerning oral cancer. It belongs to a larger group of cancers called head and neck cancers. Oral cancer is cancer that develops in the tissues of the mouth or throat. The thesis the battles of bleeding kansas directly affected the civil war, and the south was fighting primarily to protect the institution of slavery doesnt work very well, because the arguments are disjointed and focused on different ideas. The aims of this thesis were to investigate any change in incidence of base of tongue. There is an uncontrollable growth of cells that invade and cause damage to tissues. Epidemiology head and neck cancer is the sixth most common cancer worldwide, representing about 6% of all new cancers 6. Mouth cancer or oral cancer may arise as a primary lesion. Oral cancer, the focus of this document, is an example of a largely preventable disease that in most instances can be linked to behaviors that include longterm tobacco use.

The digital thesis deposit has been a graduation requirement for a number of years, giving students options on how they want to post their work. Is this really for purposes of a masters thesis or ph. To study the changes in the palatine rugae pattern during various orthodontic treatment dr. Smokeless tobacco paan and gutkha consumption and its prevalence contributing toward oral cancer article pdf available march 2017 with 1,197 reads how we measure reads. The diagnosis of oral precancer and cancer remains a challenge to the dental profession osf. Risk of occurrence of oral cancer has been extensively assessed for the association with slt. Increased knowledge paves the way to a more individualized cancer treatment aiming for. Diagnostic aids in the screening of oral cancer head. The zeb family of transcription factors zeb1 and zeb2 have been demonstrated to play a role in metastatic progression of several cancers, and may also influence the initial transformation and generation of cancer stem cells.

Cancer of the oral cavity is a common malignancy in the united states and around the world. Previous research found hpv fueled a 28 percent rise in oropharyngeal cancer cases since 1988, amounting for this page is the byproduct of over five years of indexing research from the national library of medicine on natural compounds which demonstrate anticancer properties. Over eight thousand american lives are taken by oral cancer and only a fourth of these patients do not excessively drink alcohol or smoke tobacco, which are the two main causes of oral cancer the oral cancer foundation. Cdc oral cancer background papers the oral cancer foundation. Cancer of the oral cavity and cancer of the oropharynx are 2 of the most common types of cancer that develop in the head and neck region, a grouping called head and neck cancer. Lam, mph a dissertation submitted to the johns hopkins university in conformity with. The british dental association has adopted a definition of oral. The incidence of oral and oropharyngeal cancer in south. A guide for developing and enhancing community oral health programs the.